When does an IVF doctor suggest a sperm DFI test?
One of the determining factors in the quality of the sperm is the degree of DNA fragmentation or damage to the sperm. Sperm DNA fragmentation either does not relate to or has no bearing on parameters which are usually measured during a typical semen assay.
However, the methodology for fertilizing the egg-IUI insemination, in vitro fertilization, or the extent of DNA fragmentation has a strong correlation with the inability of the sperm to initiate pregnancy.
With the ability to test for sperm DNA fragmentation, even the best infertility specialist is now in a position to explain many such cases of “unexplained” infertility.
Where can I get the DFI test done?
DFI tests are usually performed in andrology labs affiliated with any reputable in vitro fertilization center. The result usually takes four to five hours, and the patient is expected to provide a semen sample at the IVF facility.
How is the DFI Test done?
SCD is a technique that includes denaturalizing the DNA strands under controlled conditions. It is applied in IVF centers to verify sperm DNA fragmentation. Sperm protein is extracted using heat and other chemicals. Under the microscope, sperm without a halo are fragmented, while normal sperm produces one when several stages are accomplished.
How do we interpret or understand the DFI test report?
Only less than 15% of sperm in a normal semen sample have DNA damage. Over 30% of the sperm in men of low reproductive potential are destroyed. The same factors that have long been known to cause male factor infertility also cause high DNA fragmentation. These include exposure to chemicals or toxins, heat, varicocele, infection, ageing, smoking, testicular cancer, radiation, and a host of other factors that raise the levels of free radicals in semen.
The best IVF specialists often ask about your medical history to correlate the DFI test result with your lifestyle criteria.
Why Tender Palm IVF & Fertility Center for Sperm Function Test (DFI) in Lucknow, India?
Tender Palm IVF & Fertility Center provides advanced Sperm Function Test (DFI) in Lucknow to assess sperm DNA integrity – crucial for male fertility. Our Lab experts uses cutting-edge technology to detect DNA fragmentation, helping tailor effective treatment plans. We ensure precise results, expert consultation, and compassionate care throughout your fertility evaluation.